Analytical System Modeling Method for SPECT Based on the Boltzmann Transport Equation

  • In single photon emission computed tomography (SPECT), accurately modeling of the physics of SPECT imaging process is essential to degrading factor compensation and image quality enhancement. In this paper, an analytical SPECT modeling method is proposed based on the theory of the Boltzmann transport equation and its Neumann series solution. The analytical model was numerically evaluated using high dimensional integration algorithm based on number theory. SPECT projection images for both uniform cylinder phantom with point source and NCAT phantom were calculated and compared with those which were generated by conventional Monte-Carlo modeling methods. Results show that the analytical modeling method demonstrates improved performance in computation accuracy and speed relative to the Monte-Carlo method, as well as the advantage that the computational results of the analytical method are free from statistical noise. Therefore, we conclude that the analytical method is more appropriate for modeling the SPECT imaging process than Monte-Carlo modeling methods.
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  • [1] . PEI Lu-Cheng, ZHANG Xiao-Ze. Monte Carlo Method and Application in Particle Transport Problem. Beijing: Sci-ence Press , 1980. 213-233(in Chinese)(裴鹿成,张孝泽.蒙特卡罗方法及其在粒子输运问题中的应用.北京:科学出版社,1980.213—233)2. Boman E, Tervo J, Vauhkonen M. Phys. Med. Biol., 2005,50: 265-2803. MA Tian-Yu, JIN Yong-Jie. Efficient Analytical Scatter Modeling in Fully 3-D Iterative Single Photon Emission Computed Tomography Reconstruction. In: IEEE Nucl.Sci. Symp. Med. Imag. Conf. Rec. Piscataway. NJ: IEEEPress, 2003. 2647-26514. MA Tian-Yu, JIN Yong-Jie. J. Tsinghua Univ. (Sci. Tech.), 2003, 43(10): 1359-1362(in Chinese)(马天予,金永杰.清华大学学报(自然科学版),2003,43(10):1359—1362)5. Harrison R L, Vannoy S D, Haynor D R et al. Preliminary Experience with the Photon History Generator Module of a Public-Domain Simulation Systems for Emission Tomog-raphy. In: IEEE Nucl. Sci. Symp. Med. Imag. Conf. Rec.Piscataway. NJ: IEEE Press, 1993. 1154-11586. Segars W P. Development and Application of the New Dy-namic NURBS-based Cardiac- Torso (NCAT) Phantom.PhD Thesis. The University of North Carolina at Chapel Hill, 2001.
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MA Tian-Yu and JIN Yong-Jie. Analytical System Modeling Method for SPECT Based on the Boltzmann Transport Equation[J]. Chinese Physics C, 2006, 30(8): 806-811.
MA Tian-Yu and JIN Yong-Jie. Analytical System Modeling Method for SPECT Based on the Boltzmann Transport Equation[J]. Chinese Physics C, 2006, 30(8): 806-811. shu
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Received: 2005-11-08
Revised: 2006-01-13
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Analytical System Modeling Method for SPECT Based on the Boltzmann Transport Equation

    Corresponding author: MA Tian-Yu,
  • Department of Engineering Physics, Tsinghua University, Beijing 100084, China

Abstract: In single photon emission computed tomography (SPECT), accurately modeling of the physics of SPECT imaging process is essential to degrading factor compensation and image quality enhancement. In this paper, an analytical SPECT modeling method is proposed based on the theory of the Boltzmann transport equation and its Neumann series solution. The analytical model was numerically evaluated using high dimensional integration algorithm based on number theory. SPECT projection images for both uniform cylinder phantom with point source and NCAT phantom were calculated and compared with those which were generated by conventional Monte-Carlo modeling methods. Results show that the analytical modeling method demonstrates improved performance in computation accuracy and speed relative to the Monte-Carlo method, as well as the advantage that the computational results of the analytical method are free from statistical noise. Therefore, we conclude that the analytical method is more appropriate for modeling the SPECT imaging process than Monte-Carlo modeling methods.

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