Preliminary research on dual-energy X-ray phase-contrast imaging

  • Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials.
  • [1] G. N. Hounsfield, Br. J. Radiol, 46(552):1016-1022(1973)
    [2] R. E. Alvarez and A. Macovski, Phys. Med. Biol, 21(5):733(1976)
    [3] L. M. Zatz, Radiology, 119(3):683-688(1976)
    [4] A. Macovski, R. Alvarez, J. H. Chan et al, Comput. Biol. Med, 6(4):325-336(1976)
    [5] R. A. Rutherford, B. R. Pullan, and I. Isherwood, Neuroradiology, 11(1):15-21(1976)
    [6] R. B.Mazess, H. S. Barden, J. P.Bisek et al, Am. J. Clin. Nutr, 51(6):1106-1112(1990)
    [7] O. L. Svendsen, J. Haarbo, C. Hassager et al, Am. J. Clin. Nutr, 57(5):608-608(1993)
    [8] P. J. Ryan, in Seminars in Nuclear Medicine, Vol.27, edited by W. B. Saunders(1997), p. 291-305
    [9] G. Di Chiro, R. A. Brooks, M. Robert et al, Radiology, 131(2):521-523(1979)
    [10] L. J. Zhang, S. Y. Wu, C. S. Poon et al. J. Comput. Assist. Tomogr, 34(6):816-824(2010)
    [11] Macdonald, R. D. Richard, In Photonics West 2001-Electronic Imaging,(International Society for Optics and Photonics, 2001), p. 31-41
    [12] Z. R. Ying, R. Naidu, and C. R. Crawford, J. X-Ray Sci. Technol, 14(4):235-256(2006)
    [13] A. Momose, T. Takeda, Y. Itai et al, Nature Med, 2(4):473-475(1996)
    [14] C. Kottler, V. Revol, R. Kaufmann et al, J. Appl. Phys, 108(11):114906(2010)
    [15] A. Momose, Jpn. J. Appl. Phys, 44(9R):6355-6367(2005)
    [16] C. David, B. Nohammer, H. H. Solak et al, Appl. Phys. Lett, 81(17):3287-3289(2002)
    [17] S. Wilkins, T. Gureyev, D. Gao et al, Nature, 384(6607):335-338(1996)
    [18] S. J. Ostlere and R. H. Gold, Clin. Orthop. Relat. Res, 271:149-163(1991)
    [19] F. Pfeiffer, T. Weitkamp, O. Bunk et al, Nature Phys, 2(4):258-261(2006)
    [20] S. H. Wang, P. O. Margie, A. Momose et al, Chin. Phys. B, 6(6):673-678(2015)
  • [1] G. N. Hounsfield, Br. J. Radiol, 46(552):1016-1022(1973)
    [2] R. E. Alvarez and A. Macovski, Phys. Med. Biol, 21(5):733(1976)
    [3] L. M. Zatz, Radiology, 119(3):683-688(1976)
    [4] A. Macovski, R. Alvarez, J. H. Chan et al, Comput. Biol. Med, 6(4):325-336(1976)
    [5] R. A. Rutherford, B. R. Pullan, and I. Isherwood, Neuroradiology, 11(1):15-21(1976)
    [6] R. B.Mazess, H. S. Barden, J. P.Bisek et al, Am. J. Clin. Nutr, 51(6):1106-1112(1990)
    [7] O. L. Svendsen, J. Haarbo, C. Hassager et al, Am. J. Clin. Nutr, 57(5):608-608(1993)
    [8] P. J. Ryan, in Seminars in Nuclear Medicine, Vol.27, edited by W. B. Saunders(1997), p. 291-305
    [9] G. Di Chiro, R. A. Brooks, M. Robert et al, Radiology, 131(2):521-523(1979)
    [10] L. J. Zhang, S. Y. Wu, C. S. Poon et al. J. Comput. Assist. Tomogr, 34(6):816-824(2010)
    [11] Macdonald, R. D. Richard, In Photonics West 2001-Electronic Imaging,(International Society for Optics and Photonics, 2001), p. 31-41
    [12] Z. R. Ying, R. Naidu, and C. R. Crawford, J. X-Ray Sci. Technol, 14(4):235-256(2006)
    [13] A. Momose, T. Takeda, Y. Itai et al, Nature Med, 2(4):473-475(1996)
    [14] C. Kottler, V. Revol, R. Kaufmann et al, J. Appl. Phys, 108(11):114906(2010)
    [15] A. Momose, Jpn. J. Appl. Phys, 44(9R):6355-6367(2005)
    [16] C. David, B. Nohammer, H. H. Solak et al, Appl. Phys. Lett, 81(17):3287-3289(2002)
    [17] S. Wilkins, T. Gureyev, D. Gao et al, Nature, 384(6607):335-338(1996)
    [18] S. J. Ostlere and R. H. Gold, Clin. Orthop. Relat. Res, 271:149-163(1991)
    [19] F. Pfeiffer, T. Weitkamp, O. Bunk et al, Nature Phys, 2(4):258-261(2006)
    [20] S. H. Wang, P. O. Margie, A. Momose et al, Chin. Phys. B, 6(6):673-678(2015)
  • 加载中

Cited by

1. Jiang, Z., He, K., Zhang, D. A review of intelligent coal gangue separation technology and equipment development[J]. International Journal of Coal Preparation and Utilization, 2023. doi: 10.1080/19392699.2023.2278029
2. Deng, S., Zhu, Y., Zhang, H. et al. A method for material decomposition and quantification with grating based phase CT[J]. PLoS ONE, 2021, 16(1 January): e0245449. doi: 10.1371/journal.pone.0245449
3. Wang, S., Zan, G., Wang, Q. et al. Preliminary demonstration of flexible dual-energy x-ray phase-contrast imaging[J]. Optical Engineering, 2019, 58(11): 114105. doi: 10.1117/1.OE.58.11.114105
4. Yang, J.-S., Kwack, M.-J., Lee, S.-Y. et al. Differential phase contrast imaging using the phase retrieval of a Hilbert transform and noise filtering by low rank method[J]. Proceedings of SPIE - The International Society for Optical Engineering, 2019. doi: 10.1117/12.2521975
5. Han, H., Sharma, Y., Zan, G. et al. Preliminary research on body composition measurement using X-ray phase contrast imaging[J]. Physica Medica, 2018. doi: 10.1016/j.ejmp.2018.06.009
6. Han, H., Hu, R., Wali, F. et al. Phase-contrast imaging for body composition measurement[J]. Physica Medica, 2017. doi: 10.1016/j.ejmp.2017.10.006
Get Citation
Hua-Jie Han, Sheng-Hao Wang, Kun Gao, Zhi-Li Wang, Can Zhang, Meng Yang, Kai Zhang and Pei-Ping Zhu. Preliminary research on dual-energy X-ray phase-contrast imaging[J]. Chinese Physics C, 2016, 40(4): 048201. doi: 10.1088/1674-1137/40/4/048201
Hua-Jie Han, Sheng-Hao Wang, Kun Gao, Zhi-Li Wang, Can Zhang, Meng Yang, Kai Zhang and Pei-Ping Zhu. Preliminary research on dual-energy X-ray phase-contrast imaging[J]. Chinese Physics C, 2016, 40(4): 048201.  doi: 10.1088/1674-1137/40/4/048201 shu
Milestone
Received: 2015-05-19
Revised: 2015-11-25
Fund

    Supported by Major State Basic Research Development Program(2012CB825800), Science Fund for Creative Research Groups(11321503) and National Natural Science Foundation of China(11179004, 10979055, 11205189, 11205157)

Article Metric

Article Views(2777)
PDF Downloads(137)
Cited by(6)
Policy on re-use
To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Email This Article

Title:
Email:

Preliminary research on dual-energy X-ray phase-contrast imaging

    Corresponding author: Kun Gao,
    Corresponding author: Kai Zhang,
  • 1. National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230027, China
  • 2. School of Engineering Science, University of Science and Technology of China, Hefei 230027, China
  • 3.  National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230027, China
  • 4.  Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China
Fund Project:  Supported by Major State Basic Research Development Program(2012CB825800), Science Fund for Creative Research Groups(11321503) and National Natural Science Foundation of China(11179004, 10979055, 11205189, 11205157)

Abstract: Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials.

    HTML

Reference (20)

目录

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return